Jennifer Rene’ Sims, 42

February 21, 1984  –  April 28, 2026

Tupelo-Jennifer Rene’ Sims, died on Tuesday, April 28, 2026 at NMMC-Tupelo after suffering a brain aneurism. She was 42 years old. Jennifer was born in Gulfport, MS. on Feb. 21, l984 to the late Reddie Sims and Myra Louise Mederious. She attended Mooreville High School. Most of her working life, she cooked with her last employment at Huddle House on Veterans Avenue. Jennifer loved her children and grandchildren, enjoying time spent with them in their activities. She was a beloved stay at home Mom for much of her life.

There will be no formal services but the family will privately celebrate her life at a later date. Holland Funeral Directors-Tupelo is honored to be serving the family.

She leaves to mourn her passing, her children Jeffrey Caldwell, Dustyn and Nash Loden, Shelby Caldwell, Keri, Morgan and Airyonna Loden and Marina Loden; her brother Joshua Mederious and her grandchildren, Meila and Miley Spencer, Aubrie Loden and Eleira Loden; a special friend, Sylvia Loden; a special companion, Alex Graham and a host of other friends.

Please follow the funeral home link above for further information, or to send online condolences or memorial gifts.